Estimating a preference-based index for a menopause specific health quality of life questionnaire
نویسندگان
چکیده
BACKGROUND The aim of the study was to develop a menopause-specific, preference-based health-related quality-of-life (HRQoL) index reflecting both menopausal symptoms and potential side-effects of Hormone Replacement Therapy (HRT). METHODS The study had three phases: the development of a health state classification, a prospective valuation survey and the estimation of a model to interpolate HRQoL indices for all remaining health states as defined by the classification. A menopausal health state classification was developed with seven dimensions: hot flushes, aching joints/muscles, anxious/frightened feelings, breast tenderness, bleeding, vaginal dryness and undesirable androgenic signs. Each dimension contains between three and five levels and defines a total of 6,075 health states. A sample of 96 health states was selected for the valuation survey. These states were valued by a sample of 229 women aged 45 to 60, randomly selected from 6 general practice lists in Sheffield, UK. Respondents were asked to complete a time trade-off (TTO) task for nine health states, resulting in an average of 16.5 values for each health state. RESULTS Mean health states valued range from 0.48 to 0.98 (where 1.0 is full health and zero is for states regarded as equivalent to death). Symptoms, as described by the classification system, can be rank-ordered in terms of their impact (from high to low) on menopausal HRQoL as follows: aching joints and muscles, bleeding, breast tenderness, anxious or frightened feelings, vaginal dryness, androgenic signs. Hot flushes did not significantly contribute to model fit. The preferred model produced a mean absolute error of 0.053, but suffered from bias at both ends of the scale. CONCLUSION This article presents an attempt to directly value a condition specific health state classification. The overall fit was disappointing, but the results demonstrate that menopausal symptoms are perceived by patients to have a significant impact on utility. The overall effect is modest compared to the more generic health state descriptions such as the EQ-5D. The resultant algorithm generates a preference-based index that can be used economic evaluation and that reflects the impact of this condition.
منابع مشابه
The Effect of Structured Educational Program by Support Group on Menopause Women’s Quality of Life
Introduction: Measuring the quality of life among menopause women is one of the efficiency proofs in health education hence, this study was conducted to determine the effect of structured educational program by support group on quality of life among menopause women. Methods: In a single blind field study from August to December 2011 in Saadatmandy health care center of Robat Karim town, 110 me...
متن کاملEvaluation of SF-36 Questionnaire Dimensions in Quality of Life of Postmenopausal Women Referring to Yazd City Health Centers in 2019
Introduction: Menopause can have negative effects on the quality of life of postmenopausal women. The main purpose of this study was to evaluate the quality of life of post-menopausal women in Yazd City, Iran. Methods: This descriptive cross-sectional study was conducted among 250 postmenopausal women over 50 years of age in Yazd. The standard SF-36 quality of life questionnaire was used to ...
متن کاملRelated factors to Menopausal women’s quality of life in Rasht
Introduction: Menopause is one of the most critical stages of women's lives and is a physiological event that occurs in middle age women between 40-59 years which results in physical, mental and social wellbeing and influences their quality of life. Paying attention to postmenopausal women’s quality of life can guarantee health for more than a third of their lifetime Objective: This stud...
متن کاملThe Relationship Between Sleep Quality and Quality of Life Among Postmenopausal Women
Background: With increased life expectancy and changes in lifespan, now women spend more years after menopause. Women with menopausal symptoms may experience a lower quality of life (QoL) and complain about poor sleep quality. This study aimed to examine the relationship between QoL and sleep quality in postmenopausal women. Methods: This research was a predictive correlational study. The stud...
متن کاملRelationship Between Health-Promoting Behaviors and Quality of Life in Postmenopausal Women
Background: Menopause is one of the most important stages of women’s life in the path of development which, comes with a series of other problems. The health status and quality of life issues of the postmenopausal women are serious challenges for many health areas. The aim of this study was to determine the relationship between health promotion behaviors and the quality of life of postmen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Health and Quality of Life Outcomes
دوره 3 شماره
صفحات -
تاریخ انتشار 2005